‘Constellation’ of post-COVID symptoms will impact global healthcare, says WHO
Far more research is needed into the “constellation” of sometimes debilitating symptoms among people who’ve recovered from COVID-19, the World Health Organization (WHO) said on Friday, adding that it “will impact” global health systems.
“We know that this post-COVID-19 condition or as patients, some patients also call it ‘long COVID’ and some clinicians call it ‘long COVID’, is a heterogenous group of symptoms that occur after the acute illness,” said Dr Janet Diaz, Team Lead, Health Care Readiness at WHO.
“So, these are symptoms or complications that can happen potentially a month after, three months after or even six months after, and as we are learning more, we are trying to understand the real duration of this condition.”
Citing reported symptoms such as neurological and physical illness, Dr Diaz noted that an unspecified number of sufferers had been unable to return to work, once they had recovered from the acute sickness caused by the new coronavirus.
“We are concerned obviously with the numbers of patients infected with SARS-CoV-2 virus that the numbers…just by the magnitude of the pandemic, will impact health systems.”
Although comprehensive data on the condition is not yet available, the WHO official insisted that “these (symptoms) were real”.
“Some of the “more common” ailments were “fatigue, exhaustion and post-exertional malaise, cognitive disfunction”, along with what some patients called “brain fog”, Dr Diaz said, describing a “constellation of symptoms”.
Further research is also needed to drill down into how many COVID-19 sufferers who did not require intensive care unit (ICU) treatment still went on to develop the condition.
“What we know this far is that patients experiencing post-COVID-19 condition could have been hospitalized patients, those in the ICU. So we do know that has happened in patients who are very sick, but also in patients who were not managed inside the hospital, those patients that were deemed to have you know what we thought as mild illness and were treated in the ambulatory outpatient setting; but in fact, they have had complications and they have had persistent symptoms or new symptoms, you know persistent symptoms, or symptoms that waxed and waned, that came and went after their acute illness.”
To promote a better understanding of post-COVID sickness and support patient care and public health interventions, the WHO has called on clinicians and patients to report data on symptoms to the Organization’s Clinical Platform.
Its case report form – which is available in multiple languages - has been designed to report standardized clinical data from individuals after they have left hospital or after acute illness.
“What we don’t know is why it’s happening, so what is the pathophysiology or (inaudible) of this condition and so the researchers are really working hard to get to the answers of these questions, you know,” Dr Diaz said.
As of Friday 12 February 2021, WHO’s coronavirus tracker reported 107,252,265 confirmed cases of COVID-19, including 2,355,339 deaths.
Regionally, the Americas have seen most cases to date, with 47,814,602 infections, followed by Europe (36,132,951), South-East Asia (13,141,859), Eastern Mediterranean (5,951,021), Africa (2,694,171) and Western Pacific (1,516,916).
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New data showing that rivers were at their lowest level for decades last year provides further evidence that the climate crisis is real and countries must act immediately to protect themselves from the increasing threat to communities and livelihoods, the UN World Meteorological Organization (WMO) said on Thursday.
The key findings from WMO’s State of Global Water Resources 2025 report covering the hydrological cycle and extreme events in the five-year period to last year:
Highlighting the long-term decline in the Earth’s freshwater storage and glacier melt, WMO Secretary-General Celeste Saulo explained that the planet’s water reserves used to act as a planetary “savings account” that absorbed the occasional dry season, avoiding a water crisis. “One of the central stories of the 2025 report is what is happening to that savings account? And the simple answer is that we are depleting it,” she told journalists in Geneva.
Groundwater reserves are equally stretched and have been in decline since 2014, WMO’s report states, with nearly two-thirds of monitored wells worldwide showing levels lower than the historical norm and indicating a shift “further toward deficit…not recovery”.
“At the same time, we are seeing more water-related disasters,” Ms. Saulo said, while also stressing that the currently strengthening El Niño “will increase the risk of drought in some areas, and flooding in others”.
Glaciers disappearing
In 2025, for the fourth consecutive year, every major glaciated region on Earth lost ice mass, leading to short-term hazards including floods and long-term water insecurity, according to WMO.
Responding to a question about whether the changing global water cycle might have contributed to the deadly Nepal-China flooding disaster, Ms. Saulo explained that melting ice and rock was just one factor in the chain of events that ultimately sent a massive and deadly wall of water and debris downstream on 26 August, killing at least 1,367 people.
“You asked if it could happen again? Absolutely; the problem in this region is that there’s 63,700 glaciers at the last count,” she told a Press Conference in Geneva. “Even if you’re looking with remote sensing with satellites at these glaciers, you might see some faults, you might see some slight shifting, that does not mean necessarily catastrophic collapse. So, in order to plan for this, it’s very, very difficult. But the international community is looking very hard at ways in which we can bring people together to solve some of these monitoring issues.”
Data indicates that glaciers shrank between 2023 and 2025 with cumulative losses of 1,400 gigatonnes of water – or about one third of annual fresh water needs.
Every major glacier region on Earth lost ice for the fourth consecutive year.
“All 19 glacier regions around the globe lost ice; in Central Asia, Iceland, the Russian Arctic and western Canada and the United States, it was among the three worst years on record,” said Wayne Jenkinson, WMO’s Director of Hydrology and Cryosphere.
Some regions with smaller glaciers such as Central Europe, the Caucasus, the western Canada and the United States may already have reached “peak water”, Mr. Jenkinson warned.
“After this point, the glacier gives less meltwater each year simply because there is less ice left to melt. That matters for every community downstream that relies on water during hot, dry summers,” he explained.
Narelle van der Wel, WMO’s Head of Cryosphere Monitoring, Predictions and Services, stressed that while some further glacier loss is unavoidable, the eventual scale of the decline is not predetermined.
“Some glacier loss is inevitable, but total loss of glaciers is not yet inevitable,” she said, pointing to emissions reductions as central to limiting future losses.
Preparing for moving baselines
The report does not attribute every observed change to climate change alone. WMO says pressure on water resources and natural variability also contribute.
Mr. Jenkinson said governments need to prepare for “moving baselines” as historical patterns become less reliable.
“The situation 30 years ago is not where we are today,” he said. Countries, he added, need to prepare “for those changes that have really already arrived”.
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